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Effect of Apixaban Pretreatment on Alteplase-Induced Thrombolysis: An In Vitro Study

Benefit of thrombolytic therapy in patients with acute stroke, who are on anticoagulant treatment, is not well addressed. The aim of this study was to investigate whether apixaban can modify the thrombolytic efficacy of alteplase in vitro. Static and flow models and two variants of red blood cell (R...

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Detalles Bibliográficos
Autores principales: Thalerová, Sandra, Pešková, Michaela, Kittová, Patrícia, Gulati, Sumeet, Víteček, Jan, Kubala, Lukáš, Mikulík, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479181/
https://www.ncbi.nlm.nih.gov/pubmed/34603054
http://dx.doi.org/10.3389/fphar.2021.740930