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Trimetazidine Attenuates Heart Failure by Improving Myocardial Metabolism via AMPK

Energic deficiency of cardiomyocytes is a dominant cause of heart failure. An antianginal agent, trimetazidine improves the myocardial energetic supply. We presumed that trimetazidine protects the cardiomyocytes from the pressure overload-induced heart failure through improving the myocardial metabo...

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Detalles Bibliográficos
Autores principales: Shu, Hongyang, Hang, Weijian, Peng, Yizhong, Nie, Jiali, Wu, Lujin, Zhang, Wenjun, Wang, Dao Wen, Zhou, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479198/
https://www.ncbi.nlm.nih.gov/pubmed/34603021
http://dx.doi.org/10.3389/fphar.2021.707399