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A structural view onto disease-linked mutations in the human neutral amino acid exchanger ASCT1
The ASCT1 transporter of the SLC1 family is largely involved in equilibration of neutral amino acids’ pools across the plasma membrane and plays a prominent role in the transport of both L- and D-isomers of serine, essential for the normal functioning of the central nervous system in mammals. A numb...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479201/ https://www.ncbi.nlm.nih.gov/pubmed/34630942 http://dx.doi.org/10.1016/j.csbj.2021.09.015 |