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A structural view onto disease-linked mutations in the human neutral amino acid exchanger ASCT1

The ASCT1 transporter of the SLC1 family is largely involved in equilibration of neutral amino acids’ pools across the plasma membrane and plays a prominent role in the transport of both L- and D-isomers of serine, essential for the normal functioning of the central nervous system in mammals. A numb...

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Detalles Bibliográficos
Autores principales: Stehantsev, Pavlo, Stetsenko, Artem, Nemchinova, Mariia, Aduri, Nanda Gowtham, Marrink, Siewert J., Gati, Cornelius, Guskov, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479201/
https://www.ncbi.nlm.nih.gov/pubmed/34630942
http://dx.doi.org/10.1016/j.csbj.2021.09.015