Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells

Folate deficiency in a fetus is well known to cause neurodevelopment defects and development disorders. A low level of folate is also thought to be a risk for depression in adults. We have previously shown that post-weaning low folate induces neuronal immaturity in the dentate gyrus in mice, which s...

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Detalles Bibliográficos
Autores principales: Araki, Ryota, Nishida, Shoji, Nakajima, Yuki, Iwakumo, Arimi, Tachioka, Hayato, Kita, Ayami, Yabe, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479244/
https://www.ncbi.nlm.nih.gov/pubmed/34622073
http://dx.doi.org/10.1016/j.heliyon.2021.e08071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479244/
https://www.ncbi.nlm.nih.gov/pubmed/34622073
http://dx.doi.org/10.1016/j.heliyon.2021.e08071

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