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Induction of cell death in ovarian cancer cells by doxorubicin and oncolytic vaccinia virus is associated with CREB3L1 activation

We have demonstrated that oncolytic vaccinia virus synergizes with doxorubicin (DOX) in inducing immunogenic cell death in platinum-resistant ovarian cancer cells and increases survival in syngeneic and xenograft tumor models. However, the mechanisms underlying the virus- and doxorubicin-mediated ca...

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Detalles Bibliográficos
Autores principales: Mistarz, Anna, Graczyk, Matthew, Winkler, Marta, Singh, Prashant K., Cortes, Eduardo, Miliotto, Anthony, Liu, Song, Long, Mark, Yan, Li, Stablewski, Aimee, O’Loughlin, Kieran, Minderman, Hans, Odunsi, Kunle, Rokita, Hanna, McGray, A.J. Robert, Zsiros, Emese, Kozbor, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479291/
https://www.ncbi.nlm.nih.gov/pubmed/34632049
http://dx.doi.org/10.1016/j.omto.2021.04.014