Modified reference based imputation and tipping point analysis in the presence of missing data due to COVID-19

In longitudinal clinical trials, missing data are inevitable due to intercurrent events (ICEs) such as treatment interruption or premature discontinuation for different reasons. The COVID-19 pandemic has had substantial impact on clinical trials since early 2020 as it may result in missing data due...

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Detalles Bibliográficos
Autores principales: Jin, Man, Liu, Ran, Robieson, Weining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479366/
https://www.ncbi.nlm.nih.gov/pubmed/34597836
http://dx.doi.org/10.1016/j.cct.2021.106575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479366/
https://www.ncbi.nlm.nih.gov/pubmed/34597836
http://dx.doi.org/10.1016/j.cct.2021.106575

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