Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis()
BACKGROUND: Evidence suggests that the outbreak of the coronavirus disease 2019 (COVID-19) and the prevention/control measures for COVID-19 may cause insomnia during the acute phase of COVID-19 pandemic in China. However, it is unclear whether insomnia sustains during the later phases of the pandemi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479411/ https://www.ncbi.nlm.nih.gov/pubmed/34732293 http://dx.doi.org/10.1016/j.sleep.2021.09.014 |
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author | Li, Yun Chen, Baixin Hong, Zhuoting Sun, Qimeng Dai, Yanyuan Basta, Maria Tang, Xiangdong Qin, Qingsong |
author_facet | Li, Yun Chen, Baixin Hong, Zhuoting Sun, Qimeng Dai, Yanyuan Basta, Maria Tang, Xiangdong Qin, Qingsong |
author_sort | Li, Yun |
collection | PubMed |
description | BACKGROUND: Evidence suggests that the outbreak of the coronavirus disease 2019 (COVID-19) and the prevention/control measures for COVID-19 may cause insomnia during the acute phase of COVID-19 pandemic in China. However, it is unclear whether insomnia sustains during the later phases of the pandemic. METHODS: We searched PubMed/Medline, EMBASE, PsycINFO and China National Knowledge Infrastructure from the 27th December 2019 to the 2nd February 2021. As early stage studies on COVID-19 pandemic in China were defined as those conducted prior to April 1st, 2020, while late stage studies were those conducted after April 1st, 2020. RESULTS: A total of 98 studies with 193,889 participants were included. The pooled prevalence of insomnia symptoms among all populations was 39.1% (95% CI 36.2–42.0%); the pooled prevalence of insomnia symptoms during the early and late stages of COVID-19 in China were 37.0% (95% CI 34.1–39.9%) and 41.8% (95% CI 33.6–50.0%), respectively. Importantly, there was no significant difference regarding the prevalence of insomnia symptoms between the early and late stages of COVID-19. Meta-regression showed that healthcare workers, COVID-19 patients, patients with chronic medical conditions and patients with mental disorders had a higher prevalence of insomnia symptoms compared to the general population. This association remained significant in healthcare workers and patients with chronic medical conditions after adjusting for age, gender, areas of high or low prevalence of COVID-19 cases, anxiety and depression. CONCLUSIONS: Over one third of our sample present insomnia symptoms during the early stage of COVID-19 pandemic in China. Interestingly, prevalence of insomnia symptoms sustains high during the late stage of the pandemic despite the control of the disease and the amelioration of its adverse effects. Our findings suggest that insomnia symptoms related to COVID-19 appear to persist of over time. |
format | Online Article Text |
id | pubmed-8479411 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84794112021-09-29 Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis() Li, Yun Chen, Baixin Hong, Zhuoting Sun, Qimeng Dai, Yanyuan Basta, Maria Tang, Xiangdong Qin, Qingsong Sleep Med Original Article BACKGROUND: Evidence suggests that the outbreak of the coronavirus disease 2019 (COVID-19) and the prevention/control measures for COVID-19 may cause insomnia during the acute phase of COVID-19 pandemic in China. However, it is unclear whether insomnia sustains during the later phases of the pandemic. METHODS: We searched PubMed/Medline, EMBASE, PsycINFO and China National Knowledge Infrastructure from the 27th December 2019 to the 2nd February 2021. As early stage studies on COVID-19 pandemic in China were defined as those conducted prior to April 1st, 2020, while late stage studies were those conducted after April 1st, 2020. RESULTS: A total of 98 studies with 193,889 participants were included. The pooled prevalence of insomnia symptoms among all populations was 39.1% (95% CI 36.2–42.0%); the pooled prevalence of insomnia symptoms during the early and late stages of COVID-19 in China were 37.0% (95% CI 34.1–39.9%) and 41.8% (95% CI 33.6–50.0%), respectively. Importantly, there was no significant difference regarding the prevalence of insomnia symptoms between the early and late stages of COVID-19. Meta-regression showed that healthcare workers, COVID-19 patients, patients with chronic medical conditions and patients with mental disorders had a higher prevalence of insomnia symptoms compared to the general population. This association remained significant in healthcare workers and patients with chronic medical conditions after adjusting for age, gender, areas of high or low prevalence of COVID-19 cases, anxiety and depression. CONCLUSIONS: Over one third of our sample present insomnia symptoms during the early stage of COVID-19 pandemic in China. Interestingly, prevalence of insomnia symptoms sustains high during the late stage of the pandemic despite the control of the disease and the amelioration of its adverse effects. Our findings suggest that insomnia symptoms related to COVID-19 appear to persist of over time. Elsevier B.V. 2022-03 2021-09-28 /pmc/articles/PMC8479411/ /pubmed/34732293 http://dx.doi.org/10.1016/j.sleep.2021.09.014 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Article Li, Yun Chen, Baixin Hong, Zhuoting Sun, Qimeng Dai, Yanyuan Basta, Maria Tang, Xiangdong Qin, Qingsong Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis() |
title | Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis() |
title_full | Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis() |
title_fullStr | Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis() |
title_full_unstemmed | Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis() |
title_short | Insomnia symptoms during the early and late stages of the COVID-19 pandemic in China: a systematic review and meta-analysis() |
title_sort | insomnia symptoms during the early and late stages of the covid-19 pandemic in china: a systematic review and meta-analysis() |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479411/ https://www.ncbi.nlm.nih.gov/pubmed/34732293 http://dx.doi.org/10.1016/j.sleep.2021.09.014 |
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