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In silico study of intrinsic dynamics of full-length apo-ACE2 and RBD-ACE2 complex

The key step for SARS-CoV-2 to infect human cells is the membrane fusion triggered by the binding of the viral extracellular Spike protein to the human extracellular receptor, the angiotensin-converting enzyme 2 (ACE2). Although the Cryo-electron microscopy (Cryo-EM) uncovered the static atomic deta...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Wang, Yuwei, Leung, Elaine Lai-Han, Yao, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479424/
https://www.ncbi.nlm.nih.gov/pubmed/34603638
http://dx.doi.org/10.1016/j.csbj.2021.09.032