Cargando…
Direct detection of the myosin super-relaxed state and interacting-heads motif in solution
The interacting-heads motif (IHM) is a structure of myosin that has been proposed to modulate cardiac output by occluding myosin molecules from undergoing the force-generating cycle. It is hypothesized to be the structural basis for the super-relaxed state (SRX), a low-ATPase kinetic state thought t...
Autores principales: | Chu, Sami, Muretta, Joseph M., Thomas, David D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479475/ https://www.ncbi.nlm.nih.gov/pubmed/34481842 http://dx.doi.org/10.1016/j.jbc.2021.101157 |
Ejemplares similares
-
Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting-heads motif and super-relaxed state of myosin
por: Rasicci, David V, et al.
Publicado: (2022) -
The role of the super-relaxed state of myosin in human metabolism
por: Wilson, Clyde, et al.
Publicado: (2020) -
To lie or not to lie: Super-relaxing with myosins
por: Nag, Suman, et al.
Publicado: (2021) -
Structural basis of the super- and hyper-relaxed states of myosin II
por: Craig, Roger, et al.
Publicado: (2021) -
Variants of the myosin interacting-heads motif
por: Padrón, Raúl, et al.
Publicado: (2022)