Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy

BACKGROUND & AIMS: Congenital tufting enteropathy (CTE) is an intractable diarrheal disease of infancy caused by mutations of epithelial cell adhesion molecule (EpCAM). The cellular and molecular basis of CTE pathology has been elusive. We hypothesized that the loss of EpCAM in CTE results in al...

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Detalles Bibliográficos
Autores principales: Das, Barun, Okamoto, Kevin, Rabalais, John, Young, Jocelyn A., Barrett, Kim E., Sivagnanam, Mamata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479479/
https://www.ncbi.nlm.nih.gov/pubmed/34198013
http://dx.doi.org/10.1016/j.jcmgh.2021.06.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479479/
https://www.ncbi.nlm.nih.gov/pubmed/34198013
http://dx.doi.org/10.1016/j.jcmgh.2021.06.015

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