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Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy
BACKGROUND & AIMS: Congenital tufting enteropathy (CTE) is an intractable diarrheal disease of infancy caused by mutations of epithelial cell adhesion molecule (EpCAM). The cellular and molecular basis of CTE pathology has been elusive. We hypothesized that the loss of EpCAM in CTE results in al...
Autores principales: | Das, Barun, Okamoto, Kevin, Rabalais, John, Young, Jocelyn A., Barrett, Kim E., Sivagnanam, Mamata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479479/ https://www.ncbi.nlm.nih.gov/pubmed/34198013 http://dx.doi.org/10.1016/j.jcmgh.2021.06.015 |
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