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Detection and utility of cell-free and circulating tumour DNA in bone and soft-tissue sarcomas

AIMS: Cell-free DNA (cfDNA) and circulating tumour DNA (ctDNA) are used for prognostication and monitoring in patients with carcinomas, but their utility is unclear in sarcomas. The objectives of this pilot study were to explore the prognostic significance of cfDNA and investigate whether tumour-spe...

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Detalles Bibliográficos
Autores principales: Tsoi, Kim M., Gokgoz, Nalan, Darville-O'Quinn, Paige, Prochazka, Patrick, Malekoltojari, Ainaz, Griffin, Anthony M., Ferguson, Peter C., Wunder, Jay S., Andrulis, Irene L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479566/
https://www.ncbi.nlm.nih.gov/pubmed/34558310
http://dx.doi.org/10.1302/2046-3758.109.BJR-2021-0014.R1