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A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi

BACKGROUND: Persistent carriage of pneumococcal vaccine serotypes has occurred after introduction of PCV13 vaccination in Africa but the mechanisms are unclear. We tested the feasibility of using a human pneumococcal challenge model in Malawi to understand immune correlates of protection against car...

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Detalles Bibliográficos
Autores principales: Morton, Ben, Burr, Sarah, Chikaonda, Tarsizio, Nsomba, Edna, Manda-Taylor, Lucinda, Henrion, Marc Y.R., Banda, Ndaziona Peter, Rylance, Jamie, Ferreira, Daniela M., Jambo, Kondwani, Gordon, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479630/
https://www.ncbi.nlm.nih.gov/pubmed/34571365
http://dx.doi.org/10.1016/j.ebiom.2021.103579