pgainsim: an R-package to assess the mode of inheritance for quantitative trait loci in GWAS

MOTIVATION: When performing genome-wide association studies conventionally the additive genetic model is used to explore whether a single nucleotide polymorphism (SNP) is associated with a quantitative trait. But for variants, which do not follow an intermediate mode of inheritance (MOI), the recess...

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Detalles Bibliográficos
Autores principales: Scherer, Nora, Sekula, Peggy, Pfaffelhuber, Peter, Schlosser, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479659/
https://www.ncbi.nlm.nih.gov/pubmed/33738486
http://dx.doi.org/10.1093/bioinformatics/btab150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479659/
https://www.ncbi.nlm.nih.gov/pubmed/33738486
http://dx.doi.org/10.1093/bioinformatics/btab150

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