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OMAmer: tree-driven and alignment-free protein assignment to subfamilies outperforms closest sequence approaches

MOTIVATION: Assigning new sequences to known protein families and subfamilies is a prerequisite for many functional, comparative and evolutionary genomics analyses. Such assignment is commonly achieved by looking for the closest sequence in a reference database, using a method such as BLAST. However...

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Detalles Bibliográficos
Autores principales: Rossier, Victor, Warwick Vesztrocy, Alex, Robinson-Rechavi, Marc, Dessimoz, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479680/
https://www.ncbi.nlm.nih.gov/pubmed/33787851
http://dx.doi.org/10.1093/bioinformatics/btab219