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Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet

Pancreatic islets are essential for maintaining physiological blood glucose levels, and declining islet function is a hallmark of type 2 diabetes. We employ mass spectrometry-based proteomics to systematically analyze islets from 9 genetic or diet-induced mouse models representing a broad cross-sect...

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Detalles Bibliográficos
Autores principales: Yau, Belinda, Naghiloo, Sheyda, Diaz-Vegas, Alexis, Carr, Austin V., Van Gerwen, Julian, Needham, Elise J., Jevon, Dillon, Chen, Sing-Young, Hoehn, Kyle L., Brandon, Amanda E., Macia, Laurance, Cooney, Gregory J., Shortreed, Michael R., Smith, Lloyd M., Keller, Mark P., Thorn, Peter, Larance, Mark, James, David E., Humphrey, Sean J., Kebede, Melkam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479695/
https://www.ncbi.nlm.nih.gov/pubmed/34622154
http://dx.doi.org/10.1016/j.isci.2021.103099