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Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet
Pancreatic islets are essential for maintaining physiological blood glucose levels, and declining islet function is a hallmark of type 2 diabetes. We employ mass spectrometry-based proteomics to systematically analyze islets from 9 genetic or diet-induced mouse models representing a broad cross-sect...
Autores principales: | Yau, Belinda, Naghiloo, Sheyda, Diaz-Vegas, Alexis, Carr, Austin V., Van Gerwen, Julian, Needham, Elise J., Jevon, Dillon, Chen, Sing-Young, Hoehn, Kyle L., Brandon, Amanda E., Macia, Laurance, Cooney, Gregory J., Shortreed, Michael R., Smith, Lloyd M., Keller, Mark P., Thorn, Peter, Larance, Mark, James, David E., Humphrey, Sean J., Kebede, Melkam A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479695/ https://www.ncbi.nlm.nih.gov/pubmed/34622154 http://dx.doi.org/10.1016/j.isci.2021.103099 |
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