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Once-monthly hemin suppresses inflammatory and autoreactive CD4(+) T cell responses to robustly ameliorate experimental rheumatoid arthritis

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that would permanently damage the affected joints. Unfortunately, a large proportion of RA patients fail to respond adequately to current treatments. Here, repurposing hemin and its ultra-long-acting formulation were explored for the ef...

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Detalles Bibliográficos
Autores principales: Sun, Bingzhi, Li, Gaojie, Guo, Ling, Yin, Na, Huang, Huan, Wu, Xiaodong, Huang, Runyue, Feng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479697/
https://www.ncbi.nlm.nih.gov/pubmed/34622156
http://dx.doi.org/10.1016/j.isci.2021.103101