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Once-monthly hemin suppresses inflammatory and autoreactive CD4(+) T cell responses to robustly ameliorate experimental rheumatoid arthritis
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that would permanently damage the affected joints. Unfortunately, a large proportion of RA patients fail to respond adequately to current treatments. Here, repurposing hemin and its ultra-long-acting formulation were explored for the ef...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479697/ https://www.ncbi.nlm.nih.gov/pubmed/34622156 http://dx.doi.org/10.1016/j.isci.2021.103101 |