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MTDH associates with m6A RNA methylation and predicts cancer response for immune checkpoint treatment

Immune checkpoint blockade (ICB) persistently provides a prognosis improvement but only in a small fraction of patients with cancer due to immunotherapy resistance induced by the consecutive activated oncogenic pathways, including MAPK, Akt, and WNT pathway partially driven by Metadherin (MTDH). How...

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Detalles Bibliográficos
Autores principales: Zhang, Fen, Huang, Huimei, Qin, Yuexiang, Chen, Changhan, She, Li, Wang, Juncheng, Huang, Donghai, Tang, Qinglai, Liu, Yong, Zhu, Gangcai, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479698/
https://www.ncbi.nlm.nih.gov/pubmed/34622157
http://dx.doi.org/10.1016/j.isci.2021.103102