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MTDH associates with m6A RNA methylation and predicts cancer response for immune checkpoint treatment
Immune checkpoint blockade (ICB) persistently provides a prognosis improvement but only in a small fraction of patients with cancer due to immunotherapy resistance induced by the consecutive activated oncogenic pathways, including MAPK, Akt, and WNT pathway partially driven by Metadherin (MTDH). How...
Autores principales: | Zhang, Fen, Huang, Huimei, Qin, Yuexiang, Chen, Changhan, She, Li, Wang, Juncheng, Huang, Donghai, Tang, Qinglai, Liu, Yong, Zhu, Gangcai, Zhang, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479698/ https://www.ncbi.nlm.nih.gov/pubmed/34622157 http://dx.doi.org/10.1016/j.isci.2021.103102 |
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