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Systems-level network modeling deciphers the master regulators of phenotypic plasticity and heterogeneity in melanoma
Phenotypic (i.e. non-genetic) heterogeneity in melanoma drives dedifferentiation, recalcitrance to targeted therapy and immunotherapy, and consequent tumor relapse and metastasis. Various markers or regulators associated with distinct phenotypes in melanoma have been identified, but, how does a netw...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479788/ https://www.ncbi.nlm.nih.gov/pubmed/34622164 http://dx.doi.org/10.1016/j.isci.2021.103111 |