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Systems-level network modeling deciphers the master regulators of phenotypic plasticity and heterogeneity in melanoma

Phenotypic (i.e. non-genetic) heterogeneity in melanoma drives dedifferentiation, recalcitrance to targeted therapy and immunotherapy, and consequent tumor relapse and metastasis. Various markers or regulators associated with distinct phenotypes in melanoma have been identified, but, how does a netw...

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Detalles Bibliográficos
Autores principales:	Pillai, Maalavika, Jolly, Mohit Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479788/ https://www.ncbi.nlm.nih.gov/pubmed/34622164 http://dx.doi.org/10.1016/j.isci.2021.103111

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