CFTR Rescue in Intestinal Organoids with GLPG/ABBV-2737, ABBV/GLPG-2222 and ABBV/GLPG-2451 Triple Therapy

Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have transformed the treatment of cystic fibrosis (CF) by targeting the basis of the disease. In particular, treatment regimen consisting of multiple compounds with complementary mechanisms of action have been shown to result in o...

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Detalles Bibliográficos
Autores principales: de Poel, Eyleen, Spelier, Sacha, Korporaal, Ricardo, Lai, Ka Wai, Boj, Sylvia F., Conrath, Katja, van der Ent, Cornelis K., Beekman, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479794/
https://www.ncbi.nlm.nih.gov/pubmed/34604301
http://dx.doi.org/10.3389/fmolb.2021.698358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479794/
https://www.ncbi.nlm.nih.gov/pubmed/34604301
http://dx.doi.org/10.3389/fmolb.2021.698358

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