Mechanically transduced immunosorbent assay to measure protein-protein interactions

Measuring protein-protein interaction (PPI) affinities is fundamental to biochemistry. Yet, conventional methods rely upon the law of mass action and cannot measure many PPIs due to a scarcity of reagents and limitations in the measurable affinity ranges. Here, we present a novel technique that leve...

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Detalles Bibliográficos
Autores principales: Petell, Christopher J, Randene, Kathyrn, Pappas, Michael, Sandoval, Diego, Strahl, Brian D, Harrison, Joseph S, Steimel, Joshua P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479797/
https://www.ncbi.nlm.nih.gov/pubmed/34581668
http://dx.doi.org/10.7554/eLife.67525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479797/
https://www.ncbi.nlm.nih.gov/pubmed/34581668
http://dx.doi.org/10.7554/eLife.67525

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