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Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice

AIMS: Gp91-containing NADPH oxidases (NOX2) are a significant source of myocardial superoxide production. An increase in NOX2 activity accompanies atrial fibrillation (AF) induction and electrical remodelling in animal models and predicts incident AF in humans; however, a direct causal role for NOX2...

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Detalles Bibliográficos
Autores principales: Mighiu, Alexandra S, Recalde, Alice, Ziberna, Klemen, Carnicer, Ricardo, Tomek, Jakub, Bub, Gil, Brewer, Alison C, Verheule, Sander, Shah, Ajay M, Simon, Jillian N, Casadei, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479801/
https://www.ncbi.nlm.nih.gov/pubmed/33483749
http://dx.doi.org/10.1093/cvr/cvab019