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Intercalation Ability of Novel Monofunctional Platinum Anticancer Drugs: A Key Step in Their Biological Action
[Image: see text] Phenanthriplatin (PtPPH) is a monovalent platinum(II)-based complex with a large cytotoxicity against cancer cells. Although the aqua-activated drug has been assumed to be the precursor for DNA damage, it is still under debate whether the way in which that metallodrug attacks to DN...
Autores principales: | Veclani, Daniele, Tolazzi, Marilena, Cerón-Carrasco, José P., Melchior, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479807/ https://www.ncbi.nlm.nih.gov/pubmed/34156233 http://dx.doi.org/10.1021/acs.jcim.1c00430 |
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