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Persistent HIV-1 transcription in CD4(+) T cells from ART-suppressed individuals can originate from biologically competent proviruses

HIV-1 is able to persist in the face of potent antiretroviral therapy (ART). A number of strategies are being explored to allow ART-free viral remission or viral eradication. In order to gauge the progress of these strategies, assays with which to measure viral reservoir size and activity are needed...

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Detalles Bibliográficos
Autores principales: Vignoles, M., Andrade, V., Noguera, M., Brander, C., Mavian, C., Salemi, M., Paredes, R., Sharkey, M., Stevenson, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479831/
https://www.ncbi.nlm.nih.gov/pubmed/34621530
http://dx.doi.org/10.1016/j.jve.2021.100053