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SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of Concern

[Image: see text] The SARS-CoV-2 spike (S) protein is exposed on the viral surface and is the first point of contact between the virus and the host. For these reasons it represents the prime target for Covid-19 vaccines. In recent months, variants of this protein have started to emerge. Their abilit...

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Detalles Bibliográficos
Autores principales: Triveri, Alice, Serapian, Stefano A., Marchetti, Filippo, Doria, Filippo, Pavoni, Silvia, Cinquini, Fabrizio, Moroni, Elisabetta, Rasola, Andrea, Frigerio, Francesco, Colombo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479857/
https://www.ncbi.nlm.nih.gov/pubmed/34468141
http://dx.doi.org/10.1021/acs.jcim.1c00857