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Local Membrane Curvature Pins and Guides Excitable Membrane Waves in Chemotactic and Macropinocytic Cells - Biomedical Insights From an Innovative Simple Model

PIP3 dynamics observed in membranes are responsible for the protruding edge formation in cancer and amoeboid cells. The mechanisms that maintain those PIP3 domains in three-dimensional space remain elusive, due to limitations in observation and analysis techniques. Recently, a strong relation betwee...

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Detalles Bibliográficos
Autores principales: Hörning, Marcel, Bullmann, Torsten, Shibata, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479871/
https://www.ncbi.nlm.nih.gov/pubmed/34604207
http://dx.doi.org/10.3389/fcell.2021.670943