An atherosclerotic plaque-targeted single-chain antibody for MR/NIR-II imaging of atherosclerosis and anti-atherosclerosis therapy

BACKGROUND: Oxidation-specific epitopes (OSEs) are rich in atherosclerotic plaques. Innate and adaptive immune responses to OSEs play an important role in atherosclerosis. The purpose of this study was to develop novel human single-chain variable fragment (scFv) antibody specific to OSEs to image an...

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Detalles Bibliográficos
Autores principales: Zhang, Liwei, Xue, Sheng, Ren, Feng, Huang, Siyang, Zhou, Ruizhi, Wang, Yu, Zhou, Changyong, Li, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479957/
https://www.ncbi.nlm.nih.gov/pubmed/34583680
http://dx.doi.org/10.1186/s12951-021-01047-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479957/
https://www.ncbi.nlm.nih.gov/pubmed/34583680
http://dx.doi.org/10.1186/s12951-021-01047-4

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