Cargando…

An atherosclerotic plaque-targeted single-chain antibody for MR/NIR-II imaging of atherosclerosis and anti-atherosclerosis therapy

BACKGROUND: Oxidation-specific epitopes (OSEs) are rich in atherosclerotic plaques. Innate and adaptive immune responses to OSEs play an important role in atherosclerosis. The purpose of this study was to develop novel human single-chain variable fragment (scFv) antibody specific to OSEs to image an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Liwei, Xue, Sheng, Ren, Feng, Huang, Siyang, Zhou, Ruizhi, Wang, Yu, Zhou, Changyong, Li, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8479957/ https://www.ncbi.nlm.nih.gov/pubmed/34583680 http://dx.doi.org/10.1186/s12951-021-01047-4

Ejemplares similares

Dendritic Cells in Human Atherosclerosis: From Circulation to Atherosclerotic Plaques
por: Van Vré, Emily A., et al.
Publicado: (2011)

A Proteomic Study of Atherosclerotic Plaques in Men with Coronary Atherosclerosis
por: Stakhneva, Ekaterina M., et al.
Publicado: (2019)

Atherosclerosis and Atheroma Plaque Rupture: Imaging Modalities in the Visualization of Vasa Vasorum and Atherosclerotic Plaques
por: Sun, Zhonghua
Publicado: (2014)

Autophagy in Atherosclerosis: A Phenomenon Found in Human Carotid Atherosclerotic Plaques
por: Liu, Huihui, et al.
Publicado: (2015)

Bacterial Communities Associated with Atherosclerotic Plaques from Russian Individuals with Atherosclerosis
por: Ziganshina, Elvira E., et al.
Publicado: (2016)

Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis
por: Preusch, Michael R, et al.
Publicado: (2016)

Plasma Testosterone Levels and Atherosclerotic Plaque Gene Expression in Men With Advanced Atherosclerosis
por: Groepenhoff, Floor, et al.
Publicado: (2021)

The Search for Associations of Serum Proteins with the Presence of Unstable Atherosclerotic Plaque in Coronary Atherosclerosis
por: Stakhneva, Ekaterina Mikhailovna, et al.
Publicado: (2022)

Gut Microbiota and Atherosclerosis—Focusing on the Plaque Stability
por: Shen, Xinyi, et al.
Publicado: (2021)

Nkx2‐5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E–Deficient Mice
por: Du, Meng, et al.
Publicado: (2016)

[(18)F]FDG Uptake in the Aortic Wall Smooth Muscle of Atherosclerotic Plaques in the Simian Atherosclerosis Model
por: Iwaki, Takayuki, et al.
Publicado: (2016)

Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques
por: Searle, Amy K., et al.
Publicado: (2021)

The Relation between Atherosclerosis Plaque Composition and Plaque Rupture
por: Babaniamansour, Parto, et al.
Publicado: (2020)

Prevalence and Characteristics of Carotid Artery High‐Risk Atherosclerotic Plaques in Chinese Patients With Cerebrovascular Symptoms: A Chinese Atherosclerosis Risk Evaluation II Study
por: Zhao, Xihai, et al.
Publicado: (2017)

Plaque features and vascular geometry in basilar artery atherosclerosis
por: Zhou, Li, et al.
Publicado: (2020)

Phage display selection of peptides that home to atherosclerotic plaques: IL-4 receptor as a candidate target in atherosclerosis
por: Hong, Hai-yan, et al.
Publicado: (2008)

Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
por: Ragino, Yu. I., et al.
Publicado: (2019)

Atherosclerosis and Atheroma Plaque Rupture: Normal Anatomy of Vasa Vasorum and Their Role Associated with Atherosclerosis
por: Sun, Zhonghua
Publicado: (2014)

Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
por: Yang, Chongbo, et al.
Publicado: (2019)

Plaque Calcification During Atherosclerosis Progression and Regression
por: Shioi, Atsushi, et al.
Publicado: (2018)

Role of sirtuins in attenuating plaque vulnerability in atherosclerosis
por: Velpuri, Prathosh, et al.
Publicado: (2023)

A Novel Biomarker of Coronary Atherosclerosis: Serum DKK1 Concentration Correlates with Coronary Artery Calcification and Atherosclerotic Plaques
por: Kim, Kwang-Il, et al.
Publicado: (2011)

The anti-inflammatory effects of exercise training promote atherosclerotic plaque stabilization in apolipoprotein E knockout mice with diabetic atherosclerosis
por: Kadoglou, N.P.E., et al.
Publicado: (2013)

Comparison of carotid atherosclerotic plaques between subjects in Northern and Southern China: a Chinese atherosclerosis risk evaluation study
por: Yang, Dandan, et al.
Publicado: (2020)

A Single-Cell Atlas of the Atherosclerotic Plaque in the Femoral Artery and the Heterogeneity in Macrophage Subtypes between Carotid and Femoral Atherosclerosis
por: Wang, Ping, et al.
Publicado: (2022)

Plaque Rupture in Coronary Atherosclerosis Is Associated With Increased Plaque Structural Stress
por: Costopoulos, Charis, et al.
Publicado: (2017)

The Chains of Ferroptosis Interact in the Whole Progression of Atherosclerosis
por: Wan, Xueqi, et al.
Publicado: (2023)

Targeted Therapy of Atherosclerosis Vulnerable Plaque by ROS-Scavenging Nanoparticles and MR/Fluorescence Dual-Modality Imaging Tracing
por: Dai, Yue, et al.
Publicado: (2022)

Correction: Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques
por: Yang, Chongbo, et al.
Publicado: (2022)

Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis
por: Skiba, D S, et al.
Publicado: (2017)

Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR(−/−) mouse model of atherosclerosis
por: Thompson, Dawn, et al.
Publicado: (2017)

Current knowledge on the mechanism of atherosclerosis and pro-atherosclerotic properties of oxysterols
por: Zmysłowski, Adam, et al.
Publicado: (2017)

Prevalence and Significance of Carotid Plaques in Patients With Coronary Atherosclerosis
por: Kwon, Taek-Geun, et al.
Publicado: (2009)

The Effect of Blood Pressure Variability on Coronary Atherosclerosis Plaques
por: Liu, Yue, et al.
Publicado: (2022)

Hypercoagulability Impairs Plaque Stability in Diabetes-Induced Atherosclerosis
por: Ambreen, Saira, et al.
Publicado: (2022)

Fibrinogen facilitates atherosclerotic formation in Sprague-Dawley rats: A rodent model of atherosclerosis
por: ZHOU, BIRONG, et al.
Publicado: (2013)

Rosiglitazone attenuates atherosclerosis and increases high-density lipoprotein function in atherosclerotic rabbits
por: LI, CHEN, et al.
Publicado: (2015)

(Pro)renin Receptor Inhibition Reduces Plasma Cholesterol and Triglycerides but Does Not Attenuate Atherosclerosis in Atherosclerotic Mice
por: Ye, Dien, et al.
Publicado: (2021)

Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice
por: Sastre, Cristina, et al.
Publicado: (2014)

Urotensin II Enhances Advanced Aortic Atherosclerosis Formation and Delays Plaque Regression in Hyperlipidemic Rabbits
por: Yu, Qingqing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6uppa4rjos5r0vl4uvb7umf0dk