Cargando…

Exosomes secreted by FNDC5-BMMSCs protect myocardial infarction by anti-inflammation and macrophage polarization via NF-κB signaling pathway and Nrf2/HO-1 axis

BACKGROUND: Exosomes are considered a substitute for stem cell-based therapy for myocardial infarction (MI). FNDC5, a transmembrane protein located in the cytoplasm, plays a crucial role in inflammation diseases and MI repair. Furthermore, our previous study found that FNDC5 pre-conditioning bone ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ning, Hongjuan, Chen, Haixu, Deng, Jingyu, Xiao, Chun, Xu, Moyan, Shan, Lina, Yang, Chao, Zhang, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480009/ https://www.ncbi.nlm.nih.gov/pubmed/34583757 http://dx.doi.org/10.1186/s13287-021-02591-4

Ejemplares similares

Effect of HO-1-modified BMMSCs on immune function in liver transplantation
por: Li, Peng, et al.
Publicado: (2022)

Intestinal Microbiota Participates in the Protective Effect of HO-1/BMMSCs on Liver Transplantation With Steatotic Liver Grafts in Rats
por: Yuan, Mengshu, et al.
Publicado: (2022)

Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NFκB Axis
por: Eid, Basma G., et al.
Publicado: (2020)

Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway
por: Ma, Tianwen, et al.
Publicado: (2022)

Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis
por: Ren, Chenghao, et al.
Publicado: (2021)

Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway
por: Wu, Jia, et al.
Publicado: (2022)

Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway
por: Zhang, Hongming, et al.
Publicado: (2019)

CircFNDC3B regulates osteoarthritis and oxidative stress by targeting miR-525-5p/HO-1 axis
por: Chen, Zizheng, et al.
Publicado: (2023)

Exosomes Derived from BMMSCs Mitigate the Hepatic Fibrosis via Anti-Pyroptosis Pathway in a Cirrhosis Model
por: Zhang, Yichi, et al.
Publicado: (2022)

Camptothecin Regulates Microglia Polarization and Exerts Neuroprotective Effects via Activating AKT/Nrf2/HO-1 and Inhibiting NF-κB Pathways In Vivo and In Vitro
por: He, Dewei, et al.
Publicado: (2021)

The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance
por: Furfaro, A. L., et al.
Publicado: (2016)

Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization
por: Li, Hongwu, et al.
Publicado: (2022)

Protective effects of CXCR3/HO-1 gene-modified BMMSCs on damaged intestinal epithelial cells: Role of the p38-MAPK signaling pathway
por: Yin, Mingli, et al.
Publicado: (2019)

Mangiferin Alleviates Ovalbumin-Induced Allergic Rhinitis via Nrf2/HO-1/NF-κB Signaling Pathways
por: Piao, Chun Hua, et al.
Publicado: (2020)

Tranilast reduces cardiomyocyte injury induced by ischemia‑reperfusion via Nrf2/HO‑1/NF‑κB signaling
por: Wang, Wei, et al.
Publicado: (2023)

Author Correction: CircFNDC3B regulates osteoarthritis and oxidative stress by targeting miR-525-5p/HO-1 axis
por: Chen, Zizheng, et al.
Publicado: (2023)

Exosomes from Adipose-Derived Stem Cells Alleviate Dexamethasone-Induced Bone Loss by Regulating the Nrf2/HO-1 Axis
por: Yao, Xue-wei, et al.
Publicado: (2023)

FNDC4 Inhibits RANKL-Induced Osteoclast Formation by Suppressing NF-κB Activation and CXCL10 Expression
por: Lv, Zheng-tao, et al.
Publicado: (2018)

Stilbene glycoside protects osteoblasts against oxidative damage via Nrf2/HO-1 and NF-κB signaling pathways
por: Cheng, Jian, et al.
Publicado: (2018)

Mangiferin Attenuates Myocardial Ischemia-Reperfusion Injury via MAPK/Nrf-2/HO-1/NF-κB In Vitro and In Vivo
por: Liu, Kun, et al.
Publicado: (2019)

Piceatannol SNEDDS Attenuates Estradiol-Induced Endometrial Hyperplasia in Rats by Modulation of NF-κB and Nrf2/HO-1 Axes
por: Binmahfouz, Lenah S., et al.
Publicado: (2022)

Sodium Danshensu Cream Promotes the Healing of Pressure Ulcers in Mice through the Nrf2/HO-1 and NF-κB Pathways
por: Yang, Fei, et al.
Publicado: (2022)

Heme Oxygenase-1-Modified BMMSCs Activate AMPK–Nrf2–FTH1 to Reduce Severe Steatotic Liver Ischemia–Reperfusion Injury
por: Tian, Xiaorong, et al.
Publicado: (2023)

Garcinone E Mitigates Oxidative Inflammatory Response and Protects against Experimental Autoimmune Hepatitis via Modulation of Nrf2/HO-1, NF-κB and TNF-α/JNK Axis
por: Mohamed, Gamal A., et al.
Publicado: (2022)

Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1
por: Liao, Hai-han, et al.
Publicado: (2017)

Scrophularia koraiensis Nakai Attenuates Allergic Airway Inflammation via Suppression of NF-κB and Enhancement of Nrf2/HO-1 Signaling
por: Jung, Tae-Yang, et al.
Publicado: (2020)

Cerevisterol Alleviates Inflammation via Suppression of MAPK/NF-κB/AP-1 and Activation of the Nrf2/HO-1 Signaling Cascade
por: Alam, Md Badrul, et al.
Publicado: (2020)

Epigallocatechin Gallate Protects against Hypoxia-Induced Inflammation in Microglia via NF-κB Suppression and Nrf-2/HO-1 Activation
por: Kim, So-Ra, et al.
Publicado: (2022)

Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO-1 and inhibiting the NF-κB signaling pathway
por: Sun, Weichao, et al.
Publicado: (2022)

Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways
por: Zhang, Hong, et al.
Publicado: (2023)

The Nrf2/HO-1 Axis as Targets for Flavanones: Neuroprotection by Pinocembrin, Naringenin, and Eriodictyol
por: Habtemariam, Solomon
Publicado: (2019)

The Nrf-2/HO-1 Signaling Axis: A Ray of Hope in Cardiovascular Diseases
por: Zhang, Xueyan, et al.
Publicado: (2020)

Evaluation of BMMSCs-EPCs sheets for repairing alveolar bone defects in ovariectomized rats
por: Wen, Yi, et al.
Publicado: (2017)

hCTLA4-Gene-Modified Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMMSCs) Maintain POSTN Secretion to Enhance the Migration Capability of Allogeneic hBMMSCs through the Integrin αvβ3/FAK/ERK Signaling Pathway
por: Song, Lei, et al.
Publicado: (2020)

Corrigendum to “Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1”
por: Liao, Hai-han, et al.
Publicado: (2021)

Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways
por: Luo, Dan, et al.
Publicado: (2017)

Mangiferin Mitigates Gastric Ulcer in Ischemia/ Reperfused Rats: Involvement of PPAR-γ, NF-κB and Nrf2/HO-1 Signaling Pathways
por: Mahmoud-Awny, Magdy, et al.
Publicado: (2015)

Ameliorative Effect of Linalool in Cisplatin-Induced Nephrotoxicity: The Role of HMGB1/TLR4/NF-κB and Nrf2/HO1 Pathways
por: Mohamed, Maged E., et al.
Publicado: (2020)

Moracin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf2/HO-1 and NF-κB/TGF-β pathway
por: Gu, Ronghe, et al.
Publicado: (2019)

TGR5 protects against cholestatic liver disease via suppressing the NF-κB pathway and activating the Nrf2/HO-1 pathway
por: Yang, Haojun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_it7ljju08m9t3fc4rchg94ubr6