Design, synthesis, and biological evaluation of symmetrical azine derivatives as novel tyrosinase inhibitors

A series of symmetrical azine derivatives containing different substituted benzyl moieties were designed, synthesized, and evaluated for their inhibitory activity against tyrosinase. The results showed that compounds 3e, 3f, 3h, 3i, 3j, and 3k possess effective tyrosinase inhibition with IC(50) valu...

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Detalles Bibliográficos
Autores principales: Karimian, Somaye, Kazemi, Fatemeh, Attarroshan, Mahshid, Gholampour, Maryam, Hemmati, Shiva, Sakhteman, Amirhossein, Behzadipour, Yasaman, Kabiri, Maryam, Iraji, Aida, Khoshneviszadeh, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480273/
https://www.ncbi.nlm.nih.gov/pubmed/34587988
http://dx.doi.org/10.1186/s13065-021-00780-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480273/
https://www.ncbi.nlm.nih.gov/pubmed/34587988
http://dx.doi.org/10.1186/s13065-021-00780-z

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