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Design, synthesis, and biological evaluation of symmetrical azine derivatives as novel tyrosinase inhibitors
A series of symmetrical azine derivatives containing different substituted benzyl moieties were designed, synthesized, and evaluated for their inhibitory activity against tyrosinase. The results showed that compounds 3e, 3f, 3h, 3i, 3j, and 3k possess effective tyrosinase inhibition with IC(50) valu...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480273/ https://www.ncbi.nlm.nih.gov/pubmed/34587988 http://dx.doi.org/10.1186/s13065-021-00780-z |