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Co-formability, solubility enhancement and stability of olanzapine co-amorphous systems produced with different co-formers

INTRODUCTION: Strategies to address the problem of poorly water-soluble drugs encompass the conversion of a crystalline drug into an amorphous form to promote its apparent solubility and dissolution. Co-amorphous systems (CAMs) incorporate low molecular mass molecules (co-formers), which are mixed w...

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Detalles Bibliográficos
Autores principales: Bastos, Ana C., Santos, Inês A., Pinto, João F., Fernandes, Ana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480635/
http://dx.doi.org/10.1080/07853890.2021.1896099