CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes

Activation of STING signaling plays an important role in anti-tumor immunity, and we previously reported the anti-tumor effects of STING through accumulation of M1-like macrophages in tumor tissue treated with a STING agonist. However, myeloid cells express SIRPα, an inhibitory receptor for phagocyt...

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Detalles Bibliográficos
Autores principales: Kosaka, Akemi, Ishibashi, Kei, Nagato, Toshihiro, Kitamura, Hidemitsu, Fujiwara, Yukio, Yasuda, Syunsuke, Nagata, Marino, Harabuchi, Shohei, Hayashi, Ryusuke, Yajima, Yuki, Ohara, Kenzo, Kumai, Takumi, Aoki, Naoko, Komohara, Yoshihiro, Oikawa, Kensuke, Harabuchi, Yasuaki, Kitada, Masahiro, Kobayashi, Hiroya, Ohkuri, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480673/
https://www.ncbi.nlm.nih.gov/pubmed/34559187
http://dx.doi.org/10.1084/jem.20200792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480673/
https://www.ncbi.nlm.nih.gov/pubmed/34559187
http://dx.doi.org/10.1084/jem.20200792

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