Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses

Identification of relevant epitopes is crucial for the development of subunit peptide vaccines inducing neutralizing and cellular immunity against SARS-CoV-2. Our aim was the characterization of epitopes in the receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein to generate a peptide vacci...

Descripción completa

Detalles Bibliográficos
Autores principales: Aparicio, Belén, Casares, Noelia, Egea, Josune, Ruiz, Marta, Llopiz, Diana, Maestro, Sheila, Olagüe, Cristina, González-Aseguinolaza, Gloria, Smerdou, Cristian, López-Díaz de Cerio, Ascensión, Inogés, Susana, Prósper, Felipe, Yuste, José R., Carmona-Torre, Francisco, Reina, Gabriel, Lasarte, Juan J., Sarobe, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480813/
https://www.ncbi.nlm.nih.gov/pubmed/34538222
http://dx.doi.org/10.1080/22221751.2021.1978823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480813/
https://www.ncbi.nlm.nih.gov/pubmed/34538222
http://dx.doi.org/10.1080/22221751.2021.1978823

Ejemplares similares