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Suppressor effect of catechol-O-methyltransferase gene in prostate cancer

Catechol-estrogens can cause genetic mutations and to counteract their oncogenicity, the catechol-O-methyltransferase (COMT) gene is capable of neutralizing these reactive compounds. In this study, we determined the functional effects and regulation of COMT in prostate cancer. Both the Cancer Genome...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yutaka, Shiina, Marisa, Maekawa, Shigekatsu, Kato, Taku, Shahryari, Varahram, Kulkarni, Priyanka, Dasgupta, Pritha, Yamamura, Soichiro, Saini, Sharanjot, Tabatabai, Z. Laura, Dahiya, Rajvir, Tanaka, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480839/
https://www.ncbi.nlm.nih.gov/pubmed/34587154
http://dx.doi.org/10.1371/journal.pone.0253877