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Genetic dissection of complex traits using hierarchical biological knowledge

Despite the growing constellation of genetic loci linked to common traits, these loci have yet to account for most heritable variation, and most act through poorly understood mechanisms. Recent machine learning (ML) systems have used hierarchical biological knowledge to associate genetic mutations w...

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Detalles Bibliográficos
Autores principales: Tanaka, Hidenori, Kreisberg, Jason F., Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480841/
https://www.ncbi.nlm.nih.gov/pubmed/34534210
http://dx.doi.org/10.1371/journal.pcbi.1009373