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Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression
Alternative splicing of the gene MAPT produces several isoforms of tau protein. Overexpression of these isoforms is characteristic of tauopathies, which are currently untreatable neurodegenerative diseases. Though non-canonical functions of tau have drawn interest, the role of tau isoforms in these...
Autores principales: | Grundman, Jennifer, Spencer, Brian, Sarsoza, Floyd, Rissman, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480850/ https://www.ncbi.nlm.nih.gov/pubmed/34587152 http://dx.doi.org/10.1371/journal.pone.0251611 |
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