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Trypanosome SL-RNA detection in blood and cerebrospinal fluid to demonstrate active gambiense human African trypanosomiasis infection

BACKGROUND: Spliced Leader (SL) trypanosome RNA is detectable only in the presence of live trypanosomes, is abundant and the Trypanozoon subgenus has a unique sequence. As previously shown in blood from Guinean human African trypanosomiasis (HAT) patients, SL-RNA is an accurate target for diagnosis....

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Detalles Bibliográficos
Autores principales: Ngay Lukusa, Ipos, Van Reet, Nick, Mumba Ngoyi, Dieudonné, Miaka, Erick Mwamba, Masumu, Justin, Patient Pyana, Pati, Mutombo, Wilfried, Ngolo, Digas, Kobo, Vincent, Akwaso, Felix, Ilunga, Médard, Kaninda, Lewis, Mutanda, Sylvain, Muamba, Dieudonné Mpoyi, Valverde Mordt, Olaf, Tarral, Antoine, Rembry, Sandra, Büscher, Philippe, Lejon, Veerle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480889/
https://www.ncbi.nlm.nih.gov/pubmed/34534223
http://dx.doi.org/10.1371/journal.pntd.0009739