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EVAP: A two-photon imaging tool to study conformational changes in endogenous Kv2 channels in live tissues

A primary goal of molecular physiology is to understand how conformational changes of proteins affect the function of cells, tissues, and organisms. Here, we describe an imaging method for measuring the conformational changes of the voltage sensors of endogenous ion channel proteins within live tiss...

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Detalles Bibliográficos
Autores principales: Thapa, Parashar, Stewart, Robert, Sepela, Rebecka J., Vivas, Oscar, Parajuli, Laxmi K., Lillya, Mark, Fletcher-Taylor, Sebastian, Cohen, Bruce E., Zito, Karen, Sack, Jon T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480965/
https://www.ncbi.nlm.nih.gov/pubmed/34581724
http://dx.doi.org/10.1085/jgp.202012858