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One-Two Punch Therapy for the Treatment of T-Cell Malignancies Involving p53-Dependent Cellular Senescence

T-cell malignancies are still difficult to treat due to a paucity of plans that target critical dependencies. Drug-induced cellular senescence provides a permanent cell cycle arrest during tumorigenesis and cancer development, particularly when combined with senolytics to promote apoptosis of senesc...

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Detalles Bibliográficos
Autores principales: Qing, Yingjie, Li, Hui, Zhao, Yunzi, Hu, Po, Wang, Xiangyuan, Yu, Xiaoxuan, Zhu, Mengyuan, Wang, Hongzheng, Wang, Zhanyu, Guo, Qinglong, Hui, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481056/
https://www.ncbi.nlm.nih.gov/pubmed/34603598
http://dx.doi.org/10.1155/2021/5529518