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Qualification of ELISA and neutralization methodologies to measure SARS-CoV-2 humoral immunity using human clinical samples

In response to the SARS-CoV-2 pandemic many vaccines have been developed and evaluated in human clinical trials. The humoral immune response magnitude, composition and efficacy of neutralizing SARS-CoV-2 are essential endpoints for these trials. Robust assays that are reproducibly precise, linear, a...

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Detalles Bibliográficos
Autores principales: Larsen, Sasha E., Berube, Bryan J., Pecor, Tiffany, Cross, Evan, Brown, Bryan P., Williams, Brittany D., Johnson, Emma, Qu, Pingping, Carter, Lauren, Wrenn, Samuel, Kepl, Elizabeth, Sydeman, Claire, King, Neil P., Baldwin, Susan L., Coler, Rhea N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481082/
https://www.ncbi.nlm.nih.gov/pubmed/34599915
http://dx.doi.org/10.1016/j.jim.2021.113160