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Phenotype and pathological significance of MCAM(+) (CD146(+)) T cell subset in psoriatic arthritis

BACKGROUND: CD146 (MCAM-melanoma cell adhesion molecule) is a cell surface adhesion molecule for Laminin 411. T cells expressing MCAM are mainly responsible for IL-17 production. IL-17 secreting T helper cells (Th17 cells) are critical for the pathogenesis of psoriatic arthritis (PsA). Here we hypot...

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Detalles Bibliográficos
Autores principales: Raychaudhuri, Smriti K., Abria, Christine, Raychaudhuri, Siba P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481216/
https://www.ncbi.nlm.nih.gov/pubmed/34491483
http://dx.doi.org/10.1007/s11033-021-06678-2