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Phenotype and pathological significance of MCAM(+) (CD146(+)) T cell subset in psoriatic arthritis
BACKGROUND: CD146 (MCAM-melanoma cell adhesion molecule) is a cell surface adhesion molecule for Laminin 411. T cells expressing MCAM are mainly responsible for IL-17 production. IL-17 secreting T helper cells (Th17 cells) are critical for the pathogenesis of psoriatic arthritis (PsA). Here we hypot...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481216/ https://www.ncbi.nlm.nih.gov/pubmed/34491483 http://dx.doi.org/10.1007/s11033-021-06678-2 |