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Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection

SidE family of Legionella effectors catalyze non-canonical phosphoribosyl-linked ubiquitination (PR-ubiquitination) of host proteins during bacterial infection. SdeA localizes predominantly to ER and partially to the Golgi apparatus, and mediates serine ubiquitination of multiple ER and Golgi protei...

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Detalles Bibliográficos
Autores principales: Liu, Yaobin, Mukherjee, Rukmini, Bonn, Florian, Colby, Thomas, Matic, Ivan, Glogger, Marius, Heilemann, Mike, Dikic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481228/
https://www.ncbi.nlm.nih.gov/pubmed/34285384
http://dx.doi.org/10.1038/s41418-021-00830-y