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Intravenous injection of cyclophilin A realizes the transient and reversible opening of barrier of neural vasculature through basigin in endothelial cells

Neural vasculature forms the blood–brain barrier against the delivery of systemically administered therapeutic drugs into parenchyma of neural tissues. Therefore, procedures to open the blood–brain barrier with minimal damage to tissues would lead to the great progress in therapeutic strategy for in...

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Detalles Bibliográficos
Autores principales: Nakada-Honda, Narumi, Cui, Dan, Matsuda, Satoshi, Ikeda, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481259/
https://www.ncbi.nlm.nih.gov/pubmed/34588482
http://dx.doi.org/10.1038/s41598-021-98163-w