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Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements

Acute myeloid leukemia (AML) with rearrangement of the lysine methyltransferase 2a gene (KMT2Ar) has adverse outcomes. However, reports on the prognostic impact of various translocations causing KMT2Ar are conflicting. Less is known about associated mutations and their prognostic impact. In a retros...

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Detalles Bibliográficos
Autores principales: Issa, Ghayas C., Zarka, Jabra, Sasaki, Koji, Qiao, Wei, Pak, Daewoo, Ning, Jing, Short, Nicholas J., Haddad, Fadi, Tang, Zhenya, Patel, Keyur P., Cuglievan, Branko, Daver, Naval, DiNardo, Courtney D., Jabbour, Elias, Kadia, Tapan, Borthakur, Gautam, Garcia-Manero, Guillermo, Konopleva, Marina, Andreeff, Michael, Kantarjian, Hagop M., Ravandi, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481264/
https://www.ncbi.nlm.nih.gov/pubmed/34588432
http://dx.doi.org/10.1038/s41408-021-00557-6